Endometrial Cancer Stem Cells: Are They a Possible Therapeutic Target?
نویسندگان
چکیده
منابع مشابه
Cancer stem cells: therapeutic targets
Cancer stem cells (CSCs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. This minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. Low proliferative rate, high self-renewing capacity, differentiatio...
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Adult stem cells have recently been identified in several types of mature tissue and it has also been suggested that stem-like cells exist in cancerous tissues. In this regard, stem-like cell subpopulations, referred to as side-population (SP) cells, have been identified in several tissue and tumor types, based on their ability to remove intracellular Hoechst 33342, a fluorescent dye. We have i...
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Cardiovascular disease remains the leading cause of morbidity and mortality in the United States and Europe. In recent years, the understanding that regenerative processes exist at the level of the myocardium, has placed stem cell research at center stage in cardiology. A stem cell is a cell that has the ability to divide (self replicate) for indefinite periods often throughout the life of the ...
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The clinical relevance of cancer stem cells (CSC) remains a major challenge for current cancer therapies, but preliminary findings indicate that specific targeting may be possible. Recent studies have shown that these tumor subpopulations promote tumor angiogenesis through the increased production of VEGF, whereas the VEGF neutralizing antibody bevacizumab specifically inhibits CSC growth. More...
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Neuroinflammation has a significant role in induce of Multiple sclerosis (MS) many approaches have been used to treat MS, but none of these methods have not been able to fully improve. One of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. Using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuroinfla...
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ژورنال
عنوان ژورنال: Current Obstetrics and Gynecology Reports
سال: 2012
ISSN: 2161-3303
DOI: 10.1007/s13669-012-0030-7